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As the COVID-19 pandemic continues after nearly two years, people continue searching for new ways to take control of their health and support overall wellness. This interest in self-care has led to increased interest in immune-strengthening strategies, including the use of dietary supplements.No supplements can prevent or treat COVID-19 or other illnesses, but a combination of healthy lifestyle practices and the responsible use of science-backed supplements can keep the immune system functioning at its best. A strong immune system is your best defense against any germs you may encounter. In addition to getting vaccinated, the preventive steps of hand-washing, mask wearing, and social distancing, plus other lifestyle factors including healthy diet, regular exercise, and quality sleep, can keep your immune system functioning at its peak.Evidence suggests that despite our best intentions to eat right and exercise, life’s daily stressors often get in our way. Many Americans face nutrition gaps in areas that directly support immune function. For example, the U.S. Department of Agriculture’s 2020-2025 Dietary Guidelines for Americans estimates that more than 90 percent are deficient in vitamin D, which is often linked to a stronger immune system. Although vitamin D can be obtained through sunlight, not everyone is able to be outdoors long enough to benefit. Few foods are a natural source of vitamin D, but dietary supplements are a prudent choice to meet the daily recommended intake. This is especially important throughout the pandemic, as several recent studies associated sufficient vitamin D levels to less severe cases of COVID-19.